TSC1

Туберозный склероз 1
Туберозный склероз 1
Идентификаторы
Символ	TSC1 ; LAM; TSC
Внешние ID	OMIM: 605284 MGI: 1929183 HomoloGene: 314 GeneCards: Ген TSC1
Функция	• protein binding; • GTPase regulator activity; • GTPase activating protein binding; • protein N-terminus binding; • chaperone binding;
Компонент клетки	• cytoplasm; • cytosol; • actin filament; • cell cortex; • membrane; • lamellipodium; • growth cone; • TSC1-TSC2 complex; • intracellular membrane-bounded organelle; • protein complex;
Биологический процесс	• kidney development; • neural tube closure; • regulation of cell-matrix adhesion; • rRNA export from nucleus; • regulation of translation; • potassium ion transport; • cell cycle arrest; • cell-matrix adhesion; • negative regulation of cell proliferation; • insulin receptor signaling pathway; • negative regulation of translation; • hippocampus development; • cerebral cortex development; • cell projection organization; • negative regulation of TOR signaling; • activation of Rho GTPase activity; • response to insulin; • myelination; • regulation of phosphoprotein phosphatase activity; • negative regulation of cell size; • regulation of protein kinase activity; • negative regulation of insulin receptor signaling pathway; • synapse organization; • protein stabilization; • protein heterooligomerization; • regulation of stress fiber assembly; • regulation of cell cycle; • positive regulation of focal adhesion assembly; • cardiac muscle cell differentiation;
	Источники: Amigo / QuickGO
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Ортологи

Гамартин, также известный как туберозный склероз 1 — белок, кодируемый у человека геном TSC1^[1].

↑ Entrez Gene: TSC1 tuberous sclerosis 1 (неопр.). Архивировано 5 декабря 2010 года.

[entrez-1] Entrez Gene: TSC1 tuberous sclerosis 1 (неопр.). Архивировано 5 декабря 2010 года.

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TSC1

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