The 1922 College Football All-Southern Team consists of college football players chosen by various organizations and writers for College Football All-Southern Teams for the 1922 Southern Conference football season. It was the first season of the Southern Conference.
Vanderbilt end Lynn Bomar and Georgia Tech running back Red Barron were the only two unanimous choices of a composite of selectors. Walter Camp picked no Southerners for his first-team All-American, but picked Bomar and Barron for his second team.