The 1964 United States House of Representatives elections in South Carolina were held on November 3, 1964, to select six Representatives for two-year terms from the state of South Carolina. The primary elections were held on June 9 and the runoff elections were held two weeks later on June 23. All five incumbents who ran were re-elected and the open seat in the 5th congressional district was retained by the Democrats. The composition of the state delegation thus remained solely Democratic.