| 2019 season | |
|---|---|
| President | Shohruh Saidov |
| Manager | Khakim Fuzailov (until 27 June) Alisher Tukhtaev (Caretaker) (from 27 June) |
| Stadium | Republican Stadium |
| Tajik League | 1st |
| Tajik Cup | Winners |
| Tajik Supercup | Winners |
| AFC Champions League | Preliminary round 2 vs AGMK |
| AFC Cup | Group Stage |
| Top goalscorer | League: Sheriddin Boboev (14) All: Sheriddin Boboev (19) |
The FC Istiklol 2019 season was Istiklol's eleventh Tajik League season. They were defending Tajik League and Cup Champions, whilst also participating in the Tajik Supercup, AFC Champions League and AFC Cup.
Istiklol defended their Tajik League and Tajik Cup titles, whilst also winning the Tajik Supercup. In continental competitions they were knocked out of the AFC Champions League at the Preliminary round 2 stage by AGMK, and then at the group stage of the AFC Cup.