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| Date | November 26, 1910 | ||||||||||||||||||
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| Stadium | A.A.A. Grounds | ||||||||||||||||||
| Location | Hamilton | ||||||||||||||||||
| Attendance | 12,000 | ||||||||||||||||||
The 2nd Grey Cup was played on November 26, 1910, before 12,000 fans at A.A.A. Grounds at Hamilton.
The University of Toronto Varsity Blues defeated the Hamilton Tigers 16–7.