In science, adversarial collaboration is a modality of collaboration wherein opposing views work together in order to jointly advance knowledge of the area under dispute. This can take the form of a scientific experiment conducted by two groups of experimenters with competing hypotheses, with the aim of constructing and implementing an experimental design in a way that satisfies both groups that there are no obvious biases or weaknesses in the experimental design.[1] Adversarial collaboration can involve a neutral moderator[2] and lead to a co-designed experiment and joint publishing of findings in order to resolve differences.[3] With its emphasis on transparency throughout the research process, adversarial collaboration has been described as sitting within the open science framework.[4]