| Amnioinfusion | |
|---|---|
| ICD-9-CM | 75.37 |
Amnioinfusion is a method in which isotonic fluid is instilled into the uterine cavity.
It was introduced in the 1960s as a means of terminating pregnancy and inducing labor in intrauterine death, but is currently used as a treatment in order to correct fetal heart rate changes caused by umbilical cord compression, indicated by variable decelerations seen on fetal heart rate monitoring. In severe cases of oligohydramnios, amnioinfusion may be performed prophylactically to prevent umbilical cord compression.[1]
It has also been used to reduce the risk of meconium aspiration syndrome, though evidence of benefit is mixed.[2][3][4] The UK National Institute of Health and Clinical Excellence (NICE) Guidelines recommend against the use of amnioinfusion in women with meconium stained amniotic fluid (MSAF).[5]
- ^ Hsu TL, Hsu TY, Tsai CC, Ou CY (December 2007). "The experience of amnioinfusion for oligohydramnios during the early second trimester". Taiwanese Journal of Obstetrics & Gynecology. 46 (4): 395–398. doi:10.1016/S1028-4559(08)60009-1. PMID 18182345.
- ^ Fraser WD, Hofmeyr J, Lede R, Faron G, Alexander S, Goffinet F, et al. (September 2005). "Amnioinfusion for the prevention of the meconium aspiration syndrome". The New England Journal of Medicine. 353 (9): 909–917. doi:10.1056/NEJMoa050223. PMID 16135835.
- ^ Edwards RK, Duff P (1999). "Prophylactic cefazolin in amnioinfusions administered for meconium-stained amniotic fluid". Infectious Diseases in Obstetrics and Gynecology. 7 (3): 153–157. doi:10.1155/S1064744999000241. PMC 1784731. PMID 10371474.
- ^ Buckley A, Middleton MC (1987). "Retinoic acid alters the keratinization of cultured rat sublingual keratinocytes in vitro". Archives of Dermatological Research. 279 (4): 257–65. doi:10.1007/BF00417325. PMID 2445304. S2CID 11942931.
- ^ Saygin D, Tabib T, Bittar HE, Valenzi E, Sembrat J, Chan SY, et al. (December 2012). "Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension". Pulmonary Circulation. 10 (1): 532–535. doi:10.1016/j.paed.2012.08.015. PMC 7052475. PMID 32166015.