Anagestone acetate

Anagestone acetate
Clinical data
Trade names	Anatropin, Neo-Novum
Other names	ORF-1658; Anapregnone acetate; 3-Deketo-6α-methyl-17α-acetoxyprogesterone; 6α-Methyl-17α-hydroxypregn-4-en-20-one acetate
Routes of; administration	By mouth
Drug class	Progestogen; Progestin; Progestogen ester
Identifiers
	IUPAC name [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-1,2,3,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate;
CAS Number	3137-73-3;
PubChem CID	252301;
ChemSpider	221058;
UNII	GNT396G9QT;
KEGG	D02932;
ChEBI	CHEBI:135575;
CompTox Dashboard (EPA)	DTXSID50953411 ;
ECHA InfoCard	100.019.578
Chemical and physical data
Formula	C24H36O3
Molar mass	372.549 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CCCC4)C;
	InChI InChI=1S/C24H36O3/c1-15-14-18-20(22(4)11-7-6-8-19(15)22)9-12-23(5)21(18)10-13-24(23,16(2)25)27-17(3)26/h8,15,18,20-21H,6-7,9-14H2,1-5H3/t15-,18+,20-,21-,22-,23-,24-/m0/s1; Key:KDLNOQQQEBKBQM-DICPTYMLSA-N;

Anagestone acetate, sold under the brand names Anatropin and Neo-Novum, is a progestin medication which was withdrawn from medical use due to carcinogenicity observed in animal studies.^[1]^[2]^[3]

^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 85–. ISBN 978-1-4757-2085-3.
^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 322–. ISBN 978-0-8155-1856-3.
^ IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (1987). IV. OESTROGEN-PROGESTIN COMBINATIONS. International Agency for Research on Cancer. Retrieved 24 June 2022.

[Elks2014-1] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 85–. ISBN 978-1-4757-2085-3.

[Publishing2013-2] William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 322–. ISBN 978-0-8155-1856-3.

[3] IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (1987). IV. OESTROGEN-PROGESTIN COMBINATIONS. International Agency for Research on Cancer. Retrieved 24 June 2022.

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Anagestone acetate

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