| Aneurysmal bone cyst | |
|---|---|
| Other names | Not recommended: Giant cell reparative granuloma of small bone, giant cell lesion of small bones[1] |
 | |
| A. X-ray: osteolytic lesion in tibia near knee. B/C/D/E. MRI with E showing fluid levels. | |
| Specialty | Orthopedics[1] |
| Symptoms | Pain, swelling, pressure related neurological symptoms[1] |
| Causes | Unknown[1] |
| Diagnostic method | Medical imaging: CT scan, X-ray, MRI, bone scan.[1] |
| Differential diagnosis | Telangiectatic osteosarcoma[1] |
| Treatment | Surgery[2] |
| Prognosis | 20-70% recur after curettage.[1] |
| Frequency | Rare,[3] ~0.15 cases per one million per year.[1] 80% age <20 years.[1] M=F[1] |
Aneurysmal bone cyst (ABC) is a non-cancerous bone tumor composed of multiple varying sizes of spaces in a bone which are filled with blood.[1][4] The term is a misnomer, as the lesion is neither an aneurysm nor a cyst.[5] It generally presents with pain and swelling in the affected bone.[1] Pressure on neighbouring tissues may cause compression effects such as neurological symptoms.[1]
The cause is unknown.[1] Diagnosis involves medical imaging.[1] CT scan and X-ray show lytic expansion lesions with clear borders.[1] MRI reveals fluid levels.[1]
Treatment is usually by curettage, bone grafting or surgically removing the part of bone.[2] 20–30% may recur, usually in the first couple of years after treatment, particularly in children.[2]
It is rare.[3] The incidence is around 0.15 cases per one million per year.[1] Aneurysmal bone cyst was first described by Jaffe and Lichtenstein in 1942.[5][6]
- ^ a b c d e f g h i j k l m n o p q r WHO Classification of Tumours Editorial Board, ed. (2020). "3. Bone tumours: simple bone cyst". Soft Tissue and Bone Tumours: WHO Classification of Tumours. Vol. 3 (5th ed.). Lyon (France): International Agency for Research on Cancer. pp. 437–439. ISBN 978-92-832-4503-2.
- ^ a b c "Bone tumours. What are Bone Tumours?". patient.info. Archived from the original on 24 April 2021. Retrieved 24 April 2021.
- ^ a b Muratori, Francesco; Mondanelli, Nicola; Rizzo, Anna Rosa; Beltrami, Giovanni; Giannotti, Stefano; Capanna, Rodolfo; Campanacci, Domenico Andrea (10 November 2019). "Aneurysmal Bone Cyst: A Review of Management". Surgical Technology International. 35: 325–335. ISSN 1090-3941. PMID 31476792.
- ^ Stevens, Kyle J.; Stevens, James A. (5 September 2020). "Aneurysmal Bone Cysts". StatPearls. StatPearls Publishing.
- ^ a b Maroldi, Roberto (2005). Imaging in Treatment Planning for Sinonasal Diseases. Springer. pp. 114–116. ISBN 9783540266310.
- ^ Tomasik, Patryk; Spindel, Jerzy; Miszczyk, Leszek; Chrobok, Adam; Koczy, Bogdan; Widuchowski, Jerzy; Mrozek, Tomasz; Matysiakiewicz, Jacek; Pilecki, Bolesław (September 2009). "Treatment and differential diagnosis of aneurysmal bone cyst based on our own experience". Ortopedia, Traumatologia, Rehabilitacja. 11 (5): 467–475. ISSN 1509-3492. PMID 19920289.