Annexation of Santo Domingo or of the Dominican Republic may refer to:
- French annexation during the Era de Francia (1795–1815)
- Haitian occupation of Santo Domingo (1822–1844)
- Annexation of the Dominican Republic to Spain (1861–1865)
- Proposed annexation of Santo Domingo by the United States (1869–1871)
This disambiguation page lists articles associated with the title Annexation of Santo Domingo.
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