Bayesian experimental design

Bayesian experimental design provides a general probability-theoretical framework from which other theories on experimental design can be derived. It is based on Bayesian inference to interpret the observations/data acquired during the experiment. This allows accounting for both any prior knowledge on the parameters to be determined as well as uncertainties in observations.

The theory of Bayesian experimental design[1] is to a certain extent based on the theory for making optimal decisions under uncertainty. The aim when designing an experiment is to maximize the expected utility of the experiment outcome. The utility is most commonly defined in terms of a measure of the accuracy of the information provided by the experiment (e.g., the Shannon information or the negative of the variance) but may also involve factors such as the financial cost of performing the experiment. What will be the optimal experiment design depends on the particular utility criterion chosen.

  1. ^ Lee, Se Yoon (2024). "Using Bayesian statistics in confirmatory clinical trials in the regulatory setting: a tutorial review". BMC Med Res Methodol. 24 (1): 110. doi:10.1186/s12874-024-02235-0. PMC 11077897. PMID 38714936.

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