Biomolecular condensate

Formation and examples of membraneless organelles

In biochemistry, biomolecular condensates are a class of membrane-less organelles and organelle subdomains, which carry out specialized functions within the cell. Unlike many organelles, biomolecular condensate composition is not controlled by a bounding membrane. Instead, condensates can form and maintain organization through a range of different processes, the most well-known of which is phase separation of proteins, RNA and other biopolymers into either colloidal emulsions, gels, liquid crystals, solid crystals or aggregates within cells.[1]

  1. ^ Garaizar, Adiran; Espinosa, Jorge R.; Joseph, Jerelle A.; Collepardo-Guevara, Rosana (2022-03-15). "Kinetic interplay between droplet maturation and coalescence modulates shape of aged protein condensates". Scientific Reports. 12 (1): 4390. Bibcode:2022NatSR..12.4390G. doi:10.1038/s41598-022-08130-2. ISSN 2045-2322. PMC 8924231. PMID 35293386.

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