&sq=Google&lang=en&file=File:Wiki_letter_w.svg){kind=small} | This article is missing information about prokaryotic blebs under the heading "membrane vesicles" -- actin's generally not involved and there are three classes by taxonomy. See bacterial outer membrane vesicles, PMID 23123555 and PMID 31942073. (September 2022) |
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In cell biology, a bleb (or snout) is a bulge of the plasma membrane of a cell, characterized by a spherical, "blister-like", bulky morphology.[2][3][4] It is characterized by the decoupling of the cytoskeleton from the plasma membrane, degrading the internal structure of the cell, allowing the flexibility required for the cell to separate into individual bulges or pockets of the intercellular matrix.[4] Most commonly, blebs are seen in apoptosis (programmed cell death), but they are also seen in other non-apoptotic functions, including apocrine secretion (cell secretion by disintegration of part of a cell). Blebbing, or zeiosis, is the formation of blebs.
- ^ Smith A, Parkes MA, Atkin-Smith GK, Tixeira R, Poon IK (2017). "Cell disassembly during apoptosis". WikiJournal of Medicine. 4 (1). doi:10.15347/wjm/2017.008.
- ^ Ponuwei GA, Dash PR (2016-12-01). "Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is Positively Regulated by the Lipid Signalling Phospholipase D2 (PLD2)". Achievements in the Life Sciences. 10 (2): 125–135. doi:10.1016/j.als.2016.11.001. ISSN 2078-1520.
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