In prokaryote nomenclature, Candidatus (abbreviated Ca.; Latin for "candidate of Roman office") is used to name prokaryotic taxa that are well characterized but yet-uncultured.[1] Contemporary sequencing approaches, such as 16S ribosomal RNA sequencing or metagenomics, provide much information about the analyzed organisms and thus allow to identify and characterize individual species. However, the majority of prokaryotic species remain uncultivable and hence inaccessible for further characterization in in vitro study. The recent discoveries of a multitude of candidate taxa has led to candidate phyla radiation expanding the tree of life through the new insights in bacterial diversity.