Cleavage furrow

In this electron micrograph of a cell, the cleavage furrow has nearly completely divided the cell.
Cilliate undergoing the last processes of binary fission, with the cleavage furrow being clearly visible.

In cell biology, the cleavage furrow is the indentation of the cell's surface that begins the progression of cleavage, by which animal and some algal cells undergo cytokinesis, the final splitting of the membrane, in the process of cell division. The same proteins responsible for muscle contraction, actin and myosin, begin the process of forming the cleavage furrow, creating an actomyosin ring. Other cytoskeletal proteins and actin binding proteins are involved in the procedure.


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