Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans
Other namesDFSP [1]
Histopathological image of dermatofibrosarcoma protuberans. Local recurrence long after the first excision. H&E stain
SpecialtyOncology Edit this on Wikidata

Dermatofibrosarcoma protuberans (DFSP)[2] is a rare locally aggressive malignant cutaneous soft-tissue sarcoma. DFSP develops in the connective tissue cells in the middle layer of the skin (dermis).[3] Estimates of the overall occurrence of DFSP in the United States are 0.8 to 4.5 cases per million persons per year.[4][5] In the United States, DFSP accounts for between 1 and 6 percent of all soft-tissue sarcomas[6] and 18 percent of all cutaneous soft-tissue sarcomas. In the Surveillance, Epidemiology and End Results (SEER) tumor registry from 1992 through 2004, DFSP was second only to Kaposi sarcoma.

  1. ^ "Dermatofibrosarcoma Protuberans Synonyms & Antonyms". Synonyms.com.
  2. ^ "NCI Dictionary of Cancer Terms". National Cancer Institute. 2011-02-02. Retrieved 2020-06-09.
  3. ^ "Dermatofibrosarcoma protuberans - Overview - Mayo Clinic". www.mayoclinic.org. Retrieved 2020-06-09.
  4. ^ Rouhani, Panta; Fletcher, Christopher D. M.; Devesa, Susan S.; Toro, Jorge R. (2008-08-01). "Cutaneous soft tissue sarcoma incidence patterns in the U.S. : an analysis of 12,114 cases". Cancer. 113 (3): 616–627. doi:10.1002/cncr.23571. ISSN 0008-543X. PMID 18618615. S2CID 23746544.
  5. ^ Kreicher, Kathryn L.; Kurlander, David E.; Gittleman, Haley R.; Barnholtz-Sloan, Jill S.; Bordeaux, Jeremy S. (January 2016). "Incidence and Survival of Primary Dermatofibrosarcoma Protuberans in the United States". Dermatologic Surgery. 42 (Suppl 1): S24–31. doi:10.1097/DSS.0000000000000300. ISSN 1524-4725. PMID 26730971. S2CID 12966671.
  6. ^ Kransdorf, M. J. (January 1995). "Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location". American Journal of Roentgenology. 164 (1): 129–134. doi:10.2214/ajr.164.1.7998525. ISSN 0361-803X. PMID 7998525.

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