Submission declined on 24 July 2024 by Mgp28 (talk).
Where to get help
How to improve a draft
You can also browse Wikipedia:Featured articles and Wikipedia:Good articles to find examples of Wikipedia's best writing on topics similar to your proposed article. Improving your odds of a speedy review To improve your odds of a faster review, tag your draft with relevant WikiProject tags using the button below. This will let reviewers know a new draft has been submitted in their area of interest. For instance, if you wrote about a female astronomer, you would want to add the Biography, Astronomy, and Women scientists tags. Editor resources
Once you save your changes using the "Publish changes" button below, you will be able to resubmit your draft for review by pressing the "Resubmit" button that will appear here. | ![]() |
OrthoRep is a hypermutation system used for the directed evolution of proteins. It was developed by the group of Chang C. Liu at the University of California, Irvine. It is one of the methods used for in vivo continuous evolution, which aims to expand the depth and scale in the evolutionary search for highly efficient proteins compared to conventional directed evolution. The method is based on a natural plasmid system in Kluveromyces lactis, which was ported to Saccharomyces cerevisiae, creating an extrachromosomal orthogonal error-prone replication system in yeast.[1]
- in-depth (not just passing mentions about the subject)
- reliable
- secondary
- independent of the subject
Make sure you add references that meet these criteria before resubmitting. Learn about mistakes to avoid when addressing this issue. If no additional references exist, the subject is not suitable for Wikipedia.