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In stereochemistry, an epimer is one of a pair of diastereomers.[1] The two epimers have opposite configuration at only one stereogenic center out of at least two.[2] All other stereogenic centers in the molecules are the same in each. Epimerization is the interconversion of one epimer to the other epimer.
Doxorubicin and epirubicin are two epimers that are used as drugs.
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Doxorubicin–epirubicin comparison
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- ^ Clayden, Jonathan; Greeves, Nick; Warren, Stuart (2012). Organic Chemistry (2nd ed.). Oxford University Press. p. 1112.
- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "Epimers". doi:10.1351/goldbook.E02167