Everglades virus | |
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CryoEM reconstruction of the Everglades Virus. EMDB entry EMD-5563[1] | |
Virus classification ![]() | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Kitrinoviricota |
Class: | Alsuviricetes |
Order: | Martellivirales |
Family: | Togaviridae |
Genus: | Alphavirus |
Species: | Everglades virus
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Everglades virus (EVEV) is an alphavirus included in the Venezuelan equine encephalitis virus complex. The virus circulates among rodents and vector mosquitoes and sometimes infects humans, causing a febrile illness with occasional neurological manifestations.[2][3] Although it is said to be rare in humans it is still debated if this is the case because of the possibility of underdiagnosing as well as being a unrecognized cause of other illnesses.[4] The virus is named after the Everglades, a region of subtropical wetlands in southern Florida. The virus is endemic to the U.S. state of Florida, where its geographic range mirrors that of the mosquito species Culex cedecei.[2] Hispid cotton rat and cotton mouse are considered important reservoir hosts of Everglades virus. Most clinical cases of infection occur in and around the city of Miami.[3] The abundance in clinical cases in certain parts of Florida comes from many factors such as population density and proximity to the hosts and their ecosystem.[5]