Back UDP-Glucuronosyltransferase German Glucuroniltransferasa Spanish گلوکورونوزیلترانسفراز Persian UDP-glukuronyylitransferaasi Finnish Glucuronosyltransférase French Glukuronosiltransferase ID Glucuronosiltransferasi Italian グルクロン酸転移酵素 Japanese Glucuronosiltransferase Portuguese Глюкуронозилтрансфераза Russian
| Glucuronosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Glucuronosyltransferase monomer, Xanthomonas campestris | |||||||||
| Identifiers | |||||||||
| EC no. | 2.4.1.17 | ||||||||
| CAS no. | 9030-08-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| UDP-glucuronosyl and UDP-glucosyl transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.[1] | |||||||||
| Identifiers | |||||||||
| Symbol | UDPGT | ||||||||
| Pfam | PF00201 | ||||||||
| InterPro | IPR002213 | ||||||||
| PROSITE | PDOC00359 | ||||||||
| SCOP2 | 1rrv / SCOPe / SUPFAM | ||||||||
| Membranome | 476 | ||||||||
| |||||||||
Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a microsomal glycosyltransferase (EC 2.4.1.17) that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction.[2][3]
Alternative names:
- glucuronyltransferase
- UDP-glucuronyl transferase
- UDP-GT
- ^ Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM (May 2004). "Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands". Biochemistry. 43 (18): 5170–5180. doi:10.1021/bi036130c. PMID 15122882.
- ^ King C, Rios G, Green M, Tephly T (2000). "UDP-glucuronosyltransferases". Curr Drug Metab. 1 (2): 143–161. doi:10.2174/1389200003339171. PMID 11465080.
- ^ "UDP-glucuronosyltransferase 1-1". Drugbank. Retrieved 21 November 2019.