Back Glikozid-hidrolaza BS Hidrolasa glicosídica Catalan Glycosidasen German Glucosidasas Spanish گلیکوزید هیدرولاز Persian Glykosidaasit Finnish Glycoside hydrolase French Glicosidases Galician Glikosida hidrolase ID Glicosidasi Italian
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In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic bonds in complex sugars.[1][2] They are extremely common enzymes, with roles in nature including degradation of biomass such as cellulose (cellulase), hemicellulose, and starch (amylase), in anti-bacterial defense strategies (e.g., lysozyme), in pathogenesis mechanisms (e.g., viral neuraminidases) and in normal cellular function (e.g., trimming mannosidases involved in N-linked glycoprotein biosynthesis). Together with glycosyltransferases, glycosidases form the major catalytic machinery for the synthesis and breakage of glycosidic bonds.[3]
- ^ Bourne, Yves; Henrissat, Bernard (2001). "Glycoside hydrolases and glycosyltransferases: families and functional modules". Current Opinion in Structural Biology. 11 (5): 593–600. doi:10.1016/s0959-440x(00)00253-0. PMID 11785761.
- ^ Henrissat, Bernard; Davies, Gideon (1997). "Structural and sequence-based classification of glycoside hydrolases". Current Opinion in Structural Biology. 7 (5): 637–644. doi:10.1016/s0959-440x(97)80072-3. PMID 9345621.
- ^ Silva, Roberto Nascimento; Steindorff, Andrei Stecca; Monteiro, Valdirene Neves (2014), "Metabolic Diversity of Trichoderma", Biotechnology and Biology of Trichoderma, Elsevier, pp. 363–376, doi:10.1016/b978-0-444-59576-8.00027-8, ISBN 978-0-444-59576-8, retrieved 2024-07-04