HBcAg

Capsid protein
Identifiers
OrganismHepatitis B virus genotype B2 (isolate Vietnam/9873/1997)
SymbolC
UniProtQ9QAB9
Search for
StructuresSwiss-model
DomainsInterPro
Hepatitis core antigen
Identifiers
SymbolHepatitis_core
PfamPF00906
InterProIPR002006
CATH7abl
SCOP27abl / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Schematic overview of the hepatitis B virus particle. HBcAg is a constituent of the nucleocapsid core (green hexagon).
The genome organisation of HBV. Some genes overlap. (ORF Core, at bottom left, encodes HBcAg.

HBcAg (core antigen) is a hepatitis B viral protein.[1][2] It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).

  1. ^ Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA". J. Clin. Microbiol. 41 (5): 1901–6. doi:10.1128/JCM.41.5.1901-1906.2003. PMC 154683. PMID 12734224.
  2. ^ Cao T, Meuleman P, Desombere I, Sällberg M, Leroux-Roels G (December 2001). "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model". J. Virol. 75 (23): 11449–56. doi:10.1128/JVI.75.23.11449-11456.2001. PMC 114731. PMID 11689626.

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