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Trade names | Forane, others |
AHFS/Drugs.com | FDA Professional Drug Information |
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Routes of administration | Inhalation |
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ECHA InfoCard | 100.043.528 |
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Formula | C3H2ClF5O |
Molar mass | 184.49 g·mol−1 |
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Isoflurane, sold under the brand name Forane among others, is a general anesthetic.[4] It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia, due to airway irritation with isoflurane.[3][5] Isoflurane is given via inhalation.[4]
Side effects of isoflurane include a decreased ability to breathe (respiratory depression), low blood pressure, and an irregular heartbeat.[3] Serious side effects can include malignant hyperthermia or high blood potassium.[4] It should not be used in patients with a history of malignant hyperthermia in either themselves or their family members.[3] It is unknown if its use during pregnancy is safe for the fetus, but use during a cesarean section appears to be safe.[3][4] Isoflurane is a halogenated ether.[6]
Isoflurane was approved for medical use in the United States in 1979.[4][7] It is on the World Health Organization's List of Essential Medicines.[8][9]