American biochemist and Nobel laureate (born 1964)
Jennifer Anne Doudna ForMemRS (;[ 1] born February 19, 1964)[ 2] is an American biochemist who has pioneered work in CRISPR gene editing , and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry , with Emmanuelle Charpentier , "for the development of a method for genome editing."[ 3] [ 4] She is the Li Ka Shing Chancellor's Chair Professor in the department of chemistry and the department of molecular and cell biology at the University of California, Berkeley . She has been an investigator with the Howard Hughes Medical Institute since 1997.[ 5]
Doudna graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also the founder and chair of the governance board of the Innovative Genomics Institute , which she co-founded in 2014.[ 6] Doudna is also a faculty scientist at Lawrence Berkeley National Laboratory , a senior investigator at the Gladstone Institutes , and an adjunct professor of cellular and molecular pharmacology at the University of California, San Francisco (UCSF).[ 7] [ 8] [ 9] [ 10]
In 2012, Doudna and Emmanuelle Charpentier were the first to propose that CRISPR-Cas9 (enzymes from bacteria that control microbial immunity) could be used for programmable editing of genomes,[ 11] [ 12] which has been called one of the most significant discoveries in the history of biology .[ 13] Since then, Doudna has been a leading figure in what is referred to as the "CRISPR revolution" for her fundamental work and leadership in developing CRISPR-mediated genome editing .[ 11]
Dr Jennifer Doudna at the Innovative Genomics Institute
Her many other awards and fellowships include the 2000 Alan T. Waterman Award for her research on the structure of a ribozyme , as determined by X-ray crystallography[ 14] and the 2015 Breakthrough Prize in Life Sciences for CRISPR-Cas9 genome editing technology, with Charpentier.[ 15] She has been a co-recipient of the Gruber Prize in Genetics (2015),[ 16] the Tang Prize (2016),[ 17] the Canada Gairdner International Award (2016),[ 18] and the Japan Prize (2017).[ 19] She was named one of the Time 100 most influential people in 2015,[ 20] and in 2023 was inducted into the National Inventors Hall of Fame .[ 21]
^ "Pondering 'what it means to be human' on the frontier of gene editing" . The Washington Post . May 3, 2016. Archived from the original on October 15, 2020. Retrieved October 14, 2020 .
^ "Jennifer Doudna – American biochemist" . Encyclopædia Britannica Online . Archived from the original on October 7, 2020. Retrieved November 13, 2015 .
^ Wu, Katherine J.; Zimmer, Carl; Peltier, Elian (October 7, 2020). "Nobel Prize in Chemistry Awarded to 2 Scientists for Work on Genome Editing" . The New York Times . Archived from the original on October 8, 2020. Retrieved October 7, 2020 .
^ "Press release: The Nobel Prize in Chemistry 2020" . nobelprize.org . Nobel Foundation. October 7, 2020. Archived from the original on January 15, 2021. Retrieved October 7, 2020 .
^ "Curriculum Vitae (Jennifer A. Doudna)" (PDF) . Lawrence Berkeley National Laboratory. Archived (PDF) from the original on January 15, 2017. Retrieved October 24, 2017 .
^ "Jennifer Doudna" . Innovative Genomics Institute (IGI) . Retrieved December 29, 2023 .
^ Multiple sources:
"UC Berkeley's Jennifer Doudna wins 2020 Nobel Prize in Chemistry" . University of California, Berkeley. October 7, 2020. Archived from the original on October 7, 2020. Retrieved October 10, 2020 .
Langelier, Julie (September 5, 2018). "Jennifer Doudna Opens Laboratory at the Gladstone Institutes" . Gladstone Institutes . Archived from the original on October 10, 2018. Retrieved October 9, 2018 .
"Interview with Jennifer Doudna (recorded in 2004)" . National Academy of Sciences. Archived from the original on December 18, 2015. Retrieved November 8, 2017 .
^ Melissa Marino (December 1, 2004). "Biography of Jennifer A. Doudna" . Proceedings of the National Academy of Sciences of the United States of America . 101 (49): 16987–16989. Bibcode :2004PNAS..10116987M . doi :10.1073/PNAS.0408147101 . ISSN 0027-8424 . PMC 535403 . PMID 15574498 . Wikidata Q34553023 .
^ Jennifer Doudna's publications indexed by the Scopus bibliographic database. (subscription required)
^ Jennifer Doudna publications indexed by Google Scholar
^ a b Jennifer A. Doudna and Samuel H. Sternberg. A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution. Houghton Mifflin Harcourt, 2017.
^ Cite error: The named reference :0
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^ Pollack, Andrew (May 11, 2015). "Jennifer Doudna, a Pioneer Who Helped Simplify Genome Editing" . The New York Times . Archived from the original on January 2, 2022. Retrieved May 12, 2015 .
^ "Alan T. Waterman Award Recipients, 1976 – present" . National Science Foundation. Archived from the original on March 2, 2015. Retrieved October 31, 2017 .
^ "Laureates: Jennifer A. Doudna" . breakthroughprize.org . Archived from the original on April 20, 2022. Retrieved October 31, 2017 .
^ "2015 Genetics Prize: Jennifer Doudna" . The Gruber Foundation. Archived from the original on September 5, 2016. Retrieved October 24, 2017 .
^ "Laureates: Biopharmaceutical Science (2016)" . Tang Prize Foundation. Archived from the original on November 7, 2017. Retrieved November 1, 2017 .
^ "Jennifer Doudna" . Canada Gairdner Foundation. Archived from the original on June 12, 2018. Retrieved November 2, 2017 .
^ "Laureates of the Japan Prize: Jennifer A. Doudna, Ph.D." The Japan Prize Foundation. Archived from the original on November 7, 2017. Retrieved November 1, 2017 .
^ Cite error: The named reference Time100-2015
was invoked but never defined (see the help page ).
^ "2023 Inductee Jennifer Doudna | National Inventors Hall of Fame®" . www.invent.org . December 28, 2023. Retrieved December 29, 2023 .