KMBC may refer to:
- KMBC-TV, a television station (virtual channel 9) licensed to Kansas City, Missouri, United States
- KMBZ (AM), a radio station (980 AM) licensed to Kansas City, Missouri, which held the call sign KMBC from 1928 to 1967
- KZPT (FM), a radio station (99.7 FM) licensed to Kansas City, Missouri, which held the call sign KMBC-FM from 1962 to 1967
- Kentucky Mountain Bible College
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