Krukenberg tumor

Krukenberg tumor
Signet ring cell carcinoma metastasis to the ovary, also called Krukenberg tumor: Gross pathology (top, cross-section at right) and histopathology at low and high magnification. The latter shows invasive proliferation of signet-ring cells with a desmoplastic stroma.
SpecialtyOncology

A Krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast.[1] Gastric adenocarcinoma, especially at the pylorus, is the most common source.[2] Krukenberg tumors are often (over 80%)[2] found in both ovaries, consistent with its metastatic nature.[2]

  1. ^ Ackerman LV, Rosai J (2004). Rosai and Ackerman's surgical pathology. Vol. 2. St. Louis: Mosby. p. 1708. ISBN 0-323-01342-2.
  2. ^ a b c Al-Agha OM, Nicastri AD (November 2006). "An in-depth look at Krukenberg tumor: an overview". Archives of Pathology & Laboratory Medicine. 130 (11): 1725–1730. doi:10.5858/2006-130-1725-AILAKT. PMID 17076540.

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