Mepitiostane

Mepitiostane
Clinical data
Trade names	Thioderon
Other names	10364-S; Epitiostanol 17β-(1-methoxy)cyclopentyl ether; 17β-[(1-Methoxycyclopentyl)oxy]-2α,3α-epithio-5α-androstane
AHFS/Drugs.com	International Drug Names
Routes of; administration	By mouth
Drug class	Androgen; Anabolic steroid; Androgen ether; Antiestrogen
ATC code	None;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (1S,2S,4R,8S,11R,12S,15S,16S)-15-[(1-methoxycyclopentyl)oxy]-2,16-dimethyl-5-thiapentacyclo[9.7.0.02,8.04,6.012,16]octadecane;
CAS Number	21362-69-6 ;
PubChem CID	9909202;
ChemSpider	8084854 ;
UNII	O00404969K;
KEGG	D01602 ;
CompTox Dashboard (EPA)	DTXSID001016882 ;
Chemical and physical data
Formula	C25H40O2S
Molar mass	404.65 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC4(CCCC4)OC)CC[C@@H]5[C@@]3(C[C@@H]6[C@H](C5)S6)C;
	InChI InChI=1S/C25H40O2S/c1-23-13-10-19-17(7-6-16-14-20-21(28-20)15-24(16,19)2)18(23)8-9-22(23)27-25(26-3)11-4-5-12-25/h16-22H,4-15H2,1-3H3/t16-,17-,18-,19-,20-,21+,22-,23-,24-/m0/s1 ; Key:IVDYZAAPOLNZKG-KWHRADDSSA-N ;
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Mepitiostane, sold under the brand name Thioderon, is an orally active antiestrogen and anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which is marketed in Japan as an antineoplastic agent for the treatment of breast cancer.^[1]^[2]^[3]^[4]^[5] It is a prodrug of epitiostanol.^[6]^[7] The drug was patented and described in 1968.^[1]

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^ "Mepitiostane".
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^ Cite error: The named reference Stella_2007 was invoked but never defined (see the help page).
^ Borchardt RT, Smith PL, Wilson G (29 June 2013). Models for Assessing Drug Absorption and Metabolism. Springer Science & Business Media. pp. 101–. ISBN 978-1-4899-1863-5.