| Metavirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Pararnavirae |
| Phylum: | Artverviricota |
| Class: | Revtraviricetes |
| Order: | Ortervirales |
| Family: | Metaviridae |
| Genus: | Metavirus |
Metavirus is a genus of viruses in the family Metaviridae.[1] They are retrotransposons that invade a eukaryotic host genome and may only replicate once the virus has infected the host.[2] These genetic elements exist to infect and replicate in their host genome and are derived from ancestral elements unrelated from their host. Metavirus may use several different hosts for transmission, and has been found to be transmissible through ovule and pollen of some plants.[3]
Metavirus contains five families of the Ty3/Gypsy element with either one or two open-reading frames; these families are mdg1, mdg3, blastopia, 412, and micropia.[4] Each of the five families contains either one or two open-reading frames, gag3 and/or pol3.[5] There is evidence to support that amino acid deprivation in the elements host genome has frequently caused a frameshift towards the Ty3 element.[6] Metavirus corresponds with the Ogre/Tat gene lineage.[7]
- ^ "ICTV Report Metaviridae".
- ^ Siebert, C (2006). "Unintelligent Design" (PDF). Discover.
- ^ Singh, R; Finnie, R (September 1973). "Seed transmission of potato spindle tuber Metavirus through the ovule of Scopolia sinensis". Canadian Plant Disease Journal. 53: 153–154.
- ^ Nefedova, Lidia; Kim, Alexander. "Mechanisms of LTR-Retroelement Transposition: Lessons from Drosophilia melanogaster". Viruses. 9: 1–10.
- ^ Levy, Camille; et al. (2013). "Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice". Vaccine. 31 (25): 2778–2785. doi:10.1016/j.vaccine.2013.03.051. PMID 23583815.
- ^ Turkel, Sezai (June 2016). "Amino Acid Starvation Enhances Programmed Ribosomal Frameshift in Metavirus Ty3 of Saccharomyces cerevisiae". Advances in Biology. 2016: 1–6. doi:10.1155/2016/1840782.
- ^ Neumann, P; Pozarkova, D; Macas, J (2003). "Highly abundant pea LTR retrotransposon Ogre is constitutively transcribed and partially spliced". Plant Molecular Biology. 53 (3): 399–410. doi:10.1023/B:PLAN.0000006945.77043.ce. PMID 14750527. S2CID 13412101.