Back مركز تنظيم الأنيبيبات الدقيقة Arabic Centar organizacije mikrotubula BS MTOC German Centro organizador de microtúbulos Spanish Centre organisateur des microtubules French Centro organizador de microtúbulos Galician MTOC HE Središte organiziranja mikrocjevčica Croatian Centro di organizzazione dei microtubuli Italian 微小管形成中心 Japanese
The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: the organization of eukaryotic flagella and cilia and the organization of the mitotic and meiotic spindle apparatus, which separate the chromosomes during cell division. The MTOC is a major site of microtubule nucleation and can be visualized in cells by immunohistochemical detection of γ-tubulin. The morphological characteristics of MTOCs vary between the different phyla and kingdoms.[1] In animals, the two most important types of MTOCs are 1) the basal bodies associated with cilia and flagella and 2) the centrosome associated with spindle formation.
- ^ Francis, Susan; Trisha Davis (1999). The spindle pole body of Saccharomyces cerevisiae: Architecture and assembly of the core components. Vol. 49. pp. 105–132. doi:10.1016/s0070-2153(99)49006-4. ISBN 9780121531492. PMID 11005016.
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