| Minor capsid protein VP2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | VP2 | ||||||||
| Pfam | PF00761 | ||||||||
| InterPro | IPR001070 | ||||||||
| |||||||||
Minor capsid protein VP2 and minor capsid protein VP3 are viral proteins that are components of the polyomavirus capsid. Polyomavirus capsids are composed of three proteins; the major component is major capsid protein VP1, which self-assembles into pentamers that in turn self-assemble into enclosed icosahedral structures. The minor components are VP2 and VP3, which bind in the interior of the capsid.[1][2][3]
- ^ Chen XS, Stehle T, Harrison SC (June 1998). "Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry". The EMBO Journal. 17 (12): 3233–40. doi:10.1093/emboj/17.12.3233. PMC 1170661. PMID 9628860.
- ^ DeCaprio JA, Garcea RL (April 2013). "A cornucopia of human polyomaviruses". Nature Reviews. Microbiology. 11 (4): 264–76. doi:10.1038/nrmicro2992. PMC 3928796. PMID 23474680.
- ^ Schowalter RM, Buck CB (2013-08-22). "The Merkel cell polyomavirus minor capsid protein". PLOS Pathogens. 9 (8): e1003558. doi:10.1371/journal.ppat.1003558. PMC 3749969. PMID 23990782.