Clinical data | |
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Trade names | Nasonex, Asmanex, Elocon, others[1] |
Other names | LAS-41002, 9α,21-Dichloro-11β,17α-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17α-(2-furoate) |
AHFS/Drugs.com | Monograph |
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Routes of administration | Topical, inhalation (nasal spray) |
Drug class | Corticosteroid; Glucocorticoid |
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Pharmacokinetic data | |
Bioavailability | Nasal spray is virtually undetectable in plasma; but systemic availability is comparable to fluticasone[7] |
Protein binding | 98% to 99% |
Metabolism | Liver |
Elimination half-life | 5.8 hours |
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ECHA InfoCard | 100.125.600 |
Chemical and physical data | |
Formula | C22H28Cl2O4 for mometasone C27H30O6Cl2 as furoate |
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(what is this?) (verify) |
Mometasone, also known as mometasone y 3 s, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma.[8][9][10] Specifically it is used to prevent rather than treat asthma attacks.[8] It can be applied to the skin, inhaled, or used in the nose.[8][9][10] Mometasone furoate, not mometasone, is used in medical products.[11]
Common side effects when used for asthma include asthma and thrush.[8] It is therefore recommended to rinse the mouth after use.[8] Long-term use may increase the risk for glaucoma and cataracts.[8] Common side effects when used in the nose include upper respiratory tract infections and nose bleeds.[10] Common side effects when applied on the skin include acne, skin atrophy, and itchiness.[9] It works by decreasing inflammation.[8]
Mometasone furoate was patented in 1981 and came into medical use in 1987.[12] It is on the World Health Organization's List of Essential Medicines[13] and is available as a generic medication.[14][15] In 2021, it was the 266th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[16][17]
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