Back جينوم معلوماتية الفئران Arabic معلومات چينوم الفار ARZ Mouse Genome Informatics AST Informatika o mišjem genomu BS Mouse Genome Informatics German Mouse Genome Informatics Spanish انفورماتیک ژنوم موش Persian Mouse Genome Informatics Galician Mouse Genome Informatics Dutch Informatika mišjeg genoma Serbo-Croatian

Mouse Genome Informatics

Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).[1] MGI provides access to data on the genetics, genomics and biology of the laboratory mouse to facilitate the study of human health and disease.[2][3] The database integrates multiple projects, with the two largest contributions coming from the Mouse Genome Database and Mouse Gene Expression Database (GXD).[4] As of 2018, MGI contains data curated from over 230,000 publications.[5]

The MGI resource was first published online in 1994[5] and is a collection of data, tools, and analyses created and tailored for use in the laboratory mouse, a widely used model organism. It is "the authoritative source of official names for mouse genes, alleles, and strains", which follow the guidelines established by the International Committee on Standardized Genetic Nomenclature for Mice.[6] The history and focus of Jackson Laboratory research and production facilities generates tremendous knowledge and depth which researchers can mine to advance their research. A dedicated community of mouse researchers, worldwide enhances and contributes to the knowledge as well. This is an indispensable tool for any researcher using the mouse as a model organism for their research, and for researchers interested in genes that share homology with the mouse genes. Various mouse research support resources including animal collections and free colony management software are also available at the MGI site.[7]

  1. ^ "MGI-MGI Current Funding Support". jax.org. Retrieved 2 June 2015.
  2. ^ Shaw D (May 2004). "Searching the Mouse Genome Informatics (MGI) resources for information on mouse biology from genotype to phenotype". Current Protocols in Bioinformatics. Chapter 1: Unit 1.7. doi:10.1002/0471250953.bi0107s05. ISBN 0471250953. PMC 5147750. PMID 18428715.
  3. ^ Qi D, Blake JA, Kadin JA, Richardson JE, Ringwald M, Eppig JT, Bult CJ (8–11 August 2005). Data integration in the mouse genome informatics (MGI) database. Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE. pp. 37–8. doi:10.1109/CSBW.2005.48. ISBN 0-7695-2442-7.
  4. ^ "MGI-About the Mouse Genome Informatics database resource". jax.org. Retrieved 2 June 2015.
  5. ^ a b Law, M; Shaw, DR (2018). Mouse Genome Informatics (MGI) Is the International Resource for Information on the Laboratory Mouse. Methods in Molecular Biology. Vol. 1757. pp. 141–161. doi:10.1007/978-1-4939-7737-6_7. ISBN 978-1-4939-7736-9. PMID 29761459.
  6. ^ Mouse Nomenclature Home Page, retrieved 28 August 2016
  7. ^ Ivica Letunic. "OpenHelix: Mouse Genome Informatics (MGI)". openhelix.com. Archived from the original on 26 December 2017. Retrieved 2 June 2015.
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