Back تكون الورم الصماوي المتعدد النوع 2 Arabic Multipla endokrina neoplazija tip 2 BS Tyypin 2 multippeli endokriininen neoplasia Finnish Mnoga gruczolakowatość wewnątrzwydzielnicza typu 2 Polish Синдром Сиппла Russian Множинна ендокринна неоплазія тип 2А Ukrainian Sipple sindromi Uzbek
| MEN type 2A (Sipple syndrome) | |
|---|---|
| Other names | MEN2 |
 | |
| Bilateral pheochromocytomas associated with Multiple endocrine neoplasia type 2 | |
| Specialty | Oncology  |
Multiple endocrine neoplasia type 2 (also known as "Pheochromocytoma (codons 630 and 634) and amyloid producing medullary thyroid carcinoma",[1] "PTC syndrome,"[1] and "Sipple syndrome"[1]) is a group of medical disorders associated with tumors of the endocrine system. The tumors may be benign or malignant (cancer). They generally occur in endocrine organs (e.g. thyroid, parathyroid, and adrenals), but may also occur in endocrine tissues of organs not classically thought of as endocrine.[2] MEN2 is a sub-type of MEN (multiple endocrine neoplasia) and itself has sub-types, as discussed below. Variants in MEN2A have been associated with Hirschsprung disease. Screening for this condition can begin as young as eight years old for Pheochromocytoma.
- ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ Moline J, Eng C (2011). "Multiple endocrine neoplasia type 2: an overview". Genet. Med. 13 (9): 755–64. doi:10.1097/GIM.0b013e318216cc6d. PMID 21552134. S2CID 22402472.