The exact role of Mycoplasma hominis (and to a lesser extent Ureaplasma) in regards to a number of conditions related to pregnant women and their (unborn) offspring is controversial. This is mainly because many healthy adults have genitourinary colonization with Mycoplasma, published studies on pathogenicity have important design limitations and the organisms are very difficult to detect.[1] The likelihood of colonization with M. hominis appears directly linked to the number of lifetime sexual partners[2]
Neonatal colonization does occur, but only through normal vaginal delivery. Caesarean section appears protective against colonization and is much less common. Neonatal colonization is transient.[3]
^Waites, KB; Schelonka, RL; Xiao, L; Grigsby, PL; Novy, MJ (August 2009). "Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominis". Seminars in Fetal & Neonatal Medicine. 14 (4): 190. doi:10.1016/j.siny.2008.11.009. PMID19109084.
^McCormack, WM; Almeida, PC; Bailey, PE; Grady, EM; Lee, YH (18 September 1972). "Sexual activity and vaginal colonization with genital mycoplasmas". JAMA. 221 (12): 1375–7. doi:10.1001/jama.1972.03200250017004. PMID5068553.
^Foy, HM; Kenny, GE; Levinsohn, EM; Grayston, JT (June 1970). "Acquisition of mycoplasmata and T-strains during infancy". The Journal of Infectious Diseases. 121 (6): 579–87. doi:10.1093/infdis/121.6.579. PMID4912072.