NSP2 (rotavirus) | |||||||||
---|---|---|---|---|---|---|---|---|---|
![]() | |||||||||
Identifiers | |||||||||
Symbol | Rota_NS35 | ||||||||
Pfam | PF02509 | ||||||||
InterPro | IPR003668 | ||||||||
CATH | 2gu0 | ||||||||
SCOP2 | 2r7j / SCOPe / SUPFAM | ||||||||
| |||||||||
Protein folds into two domains. |
NSP2 (NS35), is a rotavirus nonstructural RNA-binding protein that accumulates in cytoplasmic inclusions (viroplasms) and is required for genome replication.[1] NSP2 is closely associated in vivo with the viral replicase.[2] The non-structural protein NSP5 plays a role in the structure of viroplasms mediated by its interaction with NSP2.[3]