Neutral network (evolution)

A neutral network is a set of genes all related by point mutations that have equivalent function or fitness.[1] Each node represents a gene sequence and each line represents the mutation connecting two sequences. Neutral networks can be thought of as high, flat plateaus in a fitness landscape. During neutral evolution, genes can randomly move through neutral networks and traverse regions of sequence space which may have consequences for robustness and evolvability.

  1. ^ van Nimwegen, E; Crutchfield, JP; Huynen, M (Aug 17, 1999). "Neutral evolution of mutational robustness". Proceedings of the National Academy of Sciences of the United States of America. 96 (17): 9716–20. arXiv:adap-org/9903006. Bibcode:1999PNAS...96.9716V. doi:10.1073/pnas.96.17.9716. PMC 22276. PMID 10449760.

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