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Formula | C12H14ClNO |
Molar mass | 223.70 g·mol−1 |
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Norketamine, or N-desmethylketamine, is the major active metabolite of ketamine, which is formed mainly by CYP3A4.[1][2] Similarly to ketamine, norketamine acts as a noncompetitive NMDA receptor antagonist,[1][3] but is about 3–5 times less potent as an anesthetic in comparison.[2][4]