Papanicolaou stain

Papanicolaou stain showing a low-grade squamous intraepithelial lesion (LSIL) from a Pap test. Cell nuclei stained blue.

Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942.[1][2][3] The Papanicolaou stain is one of the most widely used stains in cytology,[1] where it is used to aid pathologists in making a diagnosis. Although most notable for its use in the detection of cervical cancer in the Pap test or Pap smear, it is also used to stain non-gynecological specimen preparations from a variety of bodily secretions and from small needle biopsies of organs and tissues.[4][5] Papanicolaou published three formulations of this stain in 1942, 1954, and 1960.[2]

  1. ^ a b Cite error: The named reference Schulte, 1991 was invoked but never defined (see the help page).
  2. ^ a b Cite error: The named reference Gill, 2013 was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Chantziantoniou et al., 2017 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Kumar et al., 2013 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Drury and Wallington, 1980 was invoked but never defined (see the help page).

From Wikipedia, the free encyclopedia · View on Wikipedia

Developed by Tubidy