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Trade names | Frenantol, Frenormon, Hypophenon, Paroxon, Possipione, Profenone, others |
Other names | Paraoxypropiophenone; H-365; NSC-2834; 4'-Hydroxypropiophenone; Ethyl p-hydroxyphenyl ketone; p-Propionylphenol; Paroxypropiophenone; Parahydroxypropiophenone; PHP |
Drug class | Nonsteroidal estrogen; Antigonadotropin |
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ECHA InfoCard | 100.000.676 |
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Formula | C9H10O2 |
Molar mass | 150.177 g·mol−1 |
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Paroxypropione, also known as paraoxypropiophenone, is a synthetic nonsteroidal estrogen which has been used medically as an antigonadotropin in Spain and Italy but appears to no longer be marketed.[1][2][3][4] It was first synthesized in 1902.[1] The antigonadotropic properties of the drug were discovered in 1951[3] and it entered clinical use shortly thereafter.[5]