Back بوفيدون يودي Arabic پوویدون آیوداین AZB Povidona iodada Catalan Jodovaný povidon Czech Povidon-Iod German Ιωδιούχος ποβιδόνη Greek Iodopovidona Spanish Iodopobidona Basque پوویدون آیوداین Persian Povidone iodée French
 Povidone-iodine applied to an abrasion using a cotton swab. | |
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| Trade names | Betadine, Wokadine, Pyodine, others |
| Other names | polyvidone iodine, iodopovidone |
| AHFS/Drugs.com | Consumer Drug Information |
| License data | |
| Routes of administration | Topical |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.110.412 |
| Chemical and physical data | |
| Formula | (C6H9NO)n·xI |
| Molar mass | variable |
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Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.[1][2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for.[2] It may also be used for minor wounds.[2] It may be applied to the skin as a liquid, an ointment or a powder.[2][3]
Side effects include skin irritation and sometimes swelling.[1] If used on large wounds, kidney problems, high blood sodium, and metabolic acidosis may occur.[1] It is not recommended in women who are less than 32 weeks pregnant.[2] Frequent use is not recommended in people with thyroid problems or who are taking lithium.[2]
Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine.[4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine.[4] It works by releasing iodine which results in the death of a range of microorganisms.[1]
Povidone-iodine came into commercial use in 1955.[5] It is on the World Health Organization's List of Essential Medicines.[6] Povidone-iodine is available over the counter.[7] It is sold under a number of brand names including Betadine.[2]
- ^ a b c d World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 321–323. hdl:10665/44053. ISBN 978-92-4-154765-9.
- ^ a b c d e f g British National Formulary (BNF), 69th Edition. British Medical Association; Joint Formulary Committee. 6 March 2015. p. 840. ISBN 978-0-85711-156-2. OCLC 1031488649. Archived from the original on 22 February 2022.
- ^ "Povidone iodine topical". drugs.com. Retrieved 11 May 2024.
- ^ a b Encyclopedia of polymer science and technology (3rd ed.). Wiley Publishing. 16 October 2013. p. 728. ISBN 978-0-470-07369-8. OCLC 899175361. Archived from the original on 13 January 2017.
- ^ Sneader W (31 October 2005). Drug Discovery: A History. John Wiley & Sons. p. 68. ISBN 978-0-470-01552-0. OCLC 62301847. Archived from the original on 13 January 2017.
- ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
- ^ "Povidone/iodine solution: Indications, Side Effects, Warnings - Drugs.com". www.drugs.com. Archived from the original on 13 January 2017. Retrieved 11 January 2017.