Back عوز البروتين سي Arabic Protein-C-Mangel German Déficit en protéine C French Deficit di proteina C Italian Wrodzony niedobór białka C Polish
| Protein C deficiency | |
|---|---|
| Other names | THPH3 [1] |
 | |
| This condition is inherited in an autosomal dominant manner. | |
| Specialty | Hematology  |
Protein C deficiency is a rare genetic trait that predisposes to thrombotic disease. It was first described in 1981.[2] The disease belongs to a group of genetic disorders known as thrombophilias. Protein C deficiency is associated with an increased incidence of venous thromboembolism (relative risk 8–10), whereas no association with arterial thrombotic disease has been found.[3]
- ^ "OMIM Entry - # 176860 - THROMBOPHILIA DUE TO PROTEIN C DEFICIENCY, AUTOSOMAL DOMINANT; THPH3". omim.org. Retrieved June 5, 2019.
- ^ Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C (1981). "Deficiency of protein C in congenital thrombotic disease". J. Clin. Invest. 68 (5): 1370–3. doi:10.1172/JCI110385. PMC 370934. PMID 6895379.
- ^ Khan S, Dickerman JD (2006). "Hereditary thrombophilia". Thromb J. 4 (1): 15. doi:10.1186/1477-9560-4-15. PMC 1592479. PMID 16968541.