PROS1 Identifiers Aliases PROS1 External IDs OMIM : 176880 ; MGI : 1095733 ; HomoloGene : 264 ; GeneCards : PROS1 ; OMA :PROS1 - orthologs Wikidata
Protein S (also known as PROS ) is a vitamin K -dependent plasma glycoprotein synthesized in the liver . In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP). In humans, protein S is encoded by the PROS1 gene .[ 5] [ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000184500 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022912 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Lundwall A, Dackowski W, Cohen E, Shaffer M, Mahr A, Dahlbäck B, Stenflo J, Wydro R (September 1986). "Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation" . Proc. Natl. Acad. Sci. U.S.A . 83 (18): 6716–20. Bibcode :1986PNAS...83.6716L . doi :10.1073/pnas.83.18.6716 PMC 386580 PMID 2944113 . ^ Long GL, Marshall A, Gardner JC, Naylor SL (January 1988). "Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively" . Somat. Cell Mol. Genet . 14 (1): 93–8. doi :10.1007/BF01535052 . PMID 2829367 . S2CID 31236887 . 
