| Grade I race | |
| Location | Keeneland Race Course Lexington, Kentucky, United States |
|---|---|
| Inaugurated | 1984 |
| Race type | Thoroughbred – Flat racing |
| Sponsor | Dixiana Farm (2020) |
| Website | Keeneland |
| Race information | |
| Distance | 1+1⁄8 miles |
| Surface | Turf |
| Track | Left-handed |
| Qualification | Three-year-old fillies |
| Weight | 121 lbs. |
| Purse | $750,000 (since 2024) |
The Queen Elizabeth II Challenge Cup Stakes is a Grade I American thoroughbred horse race for three-year-old fillies over a distance of one and one-eighth miles on the turf held annually in October at Keeneland Race Course in Lexington, Kentucky during the fall meeting.