RU-16117

RU-16117
Clinical data
Other names	11α-Methoxyethinylestradiol; 11α-Methoxy-17α-ethynylestradiol; 11α-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol
Routes of; administration	By mouth
Drug class	Estrogen; Estrogen ether
Identifiers
	IUPAC name (8S,9S,11R,13S,14S,17R)-17-Ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol;
CAS Number	61665-15-4;
PubChem CID	66408;
ChemSpider	59782;
CompTox Dashboard (EPA)	DTXSID60977244 ;
Chemical and physical data
Formula	C21H26O3
Molar mass	326.436 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12C[C@H]([C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O)OC;
	InChI InChI=1S/C21H26O3/c1-4-21(23)10-9-17-16-7-5-13-11-14(22)6-8-15(13)19(16)18(24-3)12-20(17,21)2/h1,6,8,11,16-19,22-23H,5,7,9-10,12H2,2-3H3/t16-,17-,18+,19+,20-,21-/m0/s1; Key:MTMZZIPTQITGCY-QHOCJJNXSA-N;

RU-16117 is an estrogen medication which was investigated for the potential treatment of symptoms of estrogen deficiency such as hot flashes and osteoporosis in women but was never marketed.^[1] It was developed for use by mouth.^[1]

^ ^a ^b ^c Raynaud JP, Azadian-Boulanger G, Bouton MM, Colin MC, Faure N, Fernand-Proulx L, et al. (April 1984). "RU 16117, an orally active estriol-like weak estrogen". Journal of Steroid Biochemistry. 20 (4B): 981–993. doi:10.1016/0022-4731(84)90008-6. PMID 6427528.

Clinical data

Other names	11α-Methoxyethinylestradiol; 11α-Methoxy-17α-ethynylestradiol; 11α-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol
Routes of administration	By mouth^[1]
Drug class	Estrogen; Estrogen ether
Identifiers
IUPAC name (8S,9S,11R,13S,14S,17R)-17-Ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
CAS Number	61665-15-4
PubChem CID	66408
ChemSpider	59782
CompTox Dashboard (EPA)	DTXSID60977244
Chemical and physical data
Formula	C₂₁H₂₆O₃
Molar mass	326.436 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@]12C[C@H]([C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O)OC
InChI InChI=1S/C21H26O3/c1-4-21(23)10-9-17-16-7-5-13-11-14(22)6-8-15(13)19(16)18(24-3)12-20(17,21)2/h1,6,8,11,16-19,22-23H,5,7,9-10,12H2,2-3H3/t16-,17-,18+,19+,20-,21-/m0/s1 Key:MTMZZIPTQITGCY-QHOCJJNXSA-N