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Names | |||
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Preferred IUPAC name
2-Hydroxybenzoic acid[1] | |||
Identifiers | |||
3D model (JSmol)
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ChEBI | |||
ChEMBL | |||
ChemSpider | |||
DrugBank | |||
ECHA InfoCard | 100.000.648 | ||
EC Number |
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KEGG | |||
PubChem CID
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RTECS number |
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UNII | |||
CompTox Dashboard (EPA)
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Properties | |||
C7H6O3 | |||
Molar mass | 138.122 g/mol | ||
Appearance | Colorless to white crystalline powder | ||
Odor | Odorless | ||
Density | 1.443 g/cm3 (20 °C)[2] | ||
Melting point | 158.6 °C (317.5 °F; 431.8 K) | ||
Boiling point | 211 °C (412 °F; 484 K) at 20 mmHg[2][3] | ||
Sublimes at 76 °C[3] | |||
Solubility | Soluble in ether, CCl4, benzene, propanol, acetone, ethanol, oil of turpentine, toluene | ||
Solubility in benzene | |||
Solubility in chloroform | |||
Solubility in methanol |
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Solubility in olive oil | 2.43 g/100 g (23 °C)[3] | ||
Solubility in acetone | 39.6 g/100 g (23 °C)[3] | ||
log P | 2.26 | ||
Vapor pressure | 10.93 mPa[3] | ||
Acidity (pKa) | |||
UV-vis (λmax) | 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)[3] | ||
−72.23·10−6 cm3/mol | |||
Refractive index (nD)
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1.565 (20 °C)[2] | ||
2.65 D | |||
Thermochemistry | |||
Std enthalpy of
formation (ΔfH⦵298) |
−589.9 kJ/mol | ||
Std enthalpy of
combustion (ΔcH⦵298) |
-3.025 MJ/mol[6] | ||
Pharmacology | |||
A01AD05 (WHO) B01AC06 (WHO) D01AE12 (WHO) N02BA01 (WHO) S01BC08 (WHO) | |||
Hazards | |||
Occupational safety and health (OHS/OSH): | |||
Eye hazards
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Severe irritation | ||
Skin hazards
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Mild irritation | ||
GHS labelling:[7] | |||
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Danger | |||
H302, H318 | |||
P280, P305+P351+P338 | |||
NFPA 704 (fire diamond) | |||
Flash point | 157 °C (315 °F; 430 K) closed cup[3] | ||
540 °C (1,004 °F; 813 K)[3] | |||
Lethal dose or concentration (LD, LC): | |||
LD50 (median dose)
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480 mg/kg (mice, oral) | ||
Safety data sheet (SDS) | MSDS[dead link] | ||
Related compounds | |||
Related compounds
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Methyl salicylate, Benzoic acid, Phenol, Aspirin, 4-Hydroxybenzoic acid, Magnesium salicylate, Choline salicylate, Bismuth subsalicylate, Sulfosalicylic acid, Salicylate synthase | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Salicylic acid is an organic compound with the formula HOC6H4COOH.[3] A colorless (or, white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin).[3] It is a plant hormone,[8] and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.[9] The name is from Latin salix for willow tree, from which it was initially identified and derived. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are known as salicylates.[3]
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: CS1 maint: DOI inactive as of April 2024 (link)