Santayana is a Spanish surname. Notable people with the surname include:
- Alfonso Pardo de Santayana y Coloma (1936–2015), Spanish military officer
- Antonio Gutiérrez de Otero y Santayana (1729–1799), Spanish lieutenant general
- George Santayana (1863–1952), Spanish-American philosopher
This page lists people with the surname Santayana.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.