Seienin (清円院) was a Japanese noble woman from the Nagao clan during the tumultuous Sengoku period. She is perhaps best known as the formal second wife of Uesugi Kagetora, also referred to as Kakeiin, and as the niece of the famed Uesugi Kenshin. She was the daughter of Aya-Gozen and sister of Uesugi Kagekatsu.[1]