Sheldon Jackson (1834–1909) was an American Presbyterian minister, missionary and government official
Sheldon Jackson may also refer to:
- Sheldon Jackson (American football) (born 1976), a former tight end for the Buffalo Bills
- Sheldon Jackson (cricketer) (born 1986), an Indian cricketer
- Sheldon Jackson College, a defunct junior college in Sitka, Alaska, named for the missionary
- Sheldon Jackson Museum, a museum located on the grounds of the former college