Something in the Water may refer to:
- Something in the Water (1944 film), a Hungarian drama film
- Something in the Water (2008 film), an Australian documentary
- Something in the Water (2024 film), a British survival thriller film
- "Something in the Water" (Brooke Fraser song)
- "Something in the Water" (Carrie Underwood song)
- "Something in the Water", a song by Tom Grennan from the album Lighting Matches
- Somethin' in the Water, a 2001 album by Jeffrey Steele
- "Somethin' in the Water", the album's title track, later recorded by Little Feat on their album Join the Band
- "Something in the Water", a song by Terri Clark from her album Just the Same