Spanish flu | |
---|---|
![]() | |
Disease | Influenza |
Virus strain | Strains of A/H1N1 |
Location | Worldwide |
Date | February 1918 – April 1920[1] |
Suspected cases‡ | 500 million (estimated)[2] |
Deaths | 25–50 million (generally accepted), other estimates range from 17 to 100 million[3][4][5] |
‡Suspected cases have not been confirmed by laboratory tests as being due to this strain, although some other strains may have been ruled out. |
Influenza (flu) |
---|
![]() |
The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 subtype of the influenza A virus. The earliest documented case was March 1918 in the state of Kansas in the United States, with further cases recorded in France, Germany and the United Kingdom in April. Two years later, nearly a third of the global population, or an estimated 500 million people, had been infected in four successive waves. Estimates of deaths range from 17 million to 50 million,[6] and possibly as high as 100 million,[7] making it one of the deadliest pandemics in history.
The pandemic broke out near the end of World War I, when wartime censors in the belligerent countries suppressed bad news to maintain morale, but newspapers freely reported the outbreak in neutral Spain, creating a false impression of Spain as the epicenter and leading to the "Spanish flu" misnomer.[8] Limited historical epidemiological data make the pandemic's geographic origin indeterminate, with competing hypotheses on the initial spread.[2]
Most influenza outbreaks disproportionately kill the young and old, with a higher survival rate in-between, but this pandemic had unusually high mortality for young adults.[9] Scientists offer several explanations for the high mortality, including a six-year climate anomaly affecting migration of disease vectors with increased likelihood of spread through bodies of water.[10] However, the claim that young adults had a high mortality during the pandemic has been contested.[11] Malnourishment, overcrowded medical camps and hospitals, and poor hygiene, exacerbated by the war, promoted bacterial superinfection, killing most of the victims after a typically prolonged death bed.[12][13]
The 1918 Spanish flu was the first of three flu pandemics caused by H1N1 influenza A virus; the others being the 1977 Russian flu and the 2009 Swine flu pandemics.[14][15][16]
NIH-NYC
was invoked but never defined (see the help page).pmid30202996
was invoked but never defined (see the help page).Friday
was invoked but never defined (see the help page).